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The U.S. Food and Drug Administration regulates zolpidem and has issued safety communications regarding next-day impairment and complex sleep behaviors.

FDA guidelines recommend:

• Using the lowest effective dose




• Avoiding alcohol




• Allowing 7–8 hours for sleep




• Discontinuing use if unusual behaviors occur

Women are often prescribed lower doses due to differences in drug metabolism. Providers carefully tailor prescriptions to individual patient needs.

Following FDA guidance minimizes risk and promotes safe outcomes.